Hi everyone! Tumblr user amagicrobot released a whole guide on how to achieve the "best" Ophelia, including skills, parents, end class, and role in the team! It's extremely insightful, and a great guide if you want to have Ophelia in an online or StreetPass team.
http://amagicrobot.tumblr.com/post/129161830448/building-the-best-ophelia