This and Deus Ex: Human Revolution are the main reasons I want to get a better computer, so yeah, definitely getting this. I love Duke Nukem 3D and I've been waiting a really long time for another (and even better) Duke FPS. From what I read, it seems they've got the Duke vibes going on right (crass, over-the-top chauvinism and such), but I'm worried about the level design and if it will be as good as Duke Nukem 3D's.
We'll see, I suppose. I hope it's as good as it should be.