[spoiler=SPOILER ABOUT NOHR LOLI]Elise dies in Hoshido, I dunno if you can prevent that.
http://www.twitch.tv/hamayama on Hamayama's stream in the Nohr ending-
[spoiler=MAJOR SPOILERS Sakura/Takumi]Sakura may die if you do something during the game... but Sakura isn't dead in the end, but Takumi is I believe RIP.